12 April 2023

Alopecia: A Flagship Solution - The Meso-Needling

Alopecia and Scalp Aging: The causes

* A Genetic Cause: Androgenic alopecia is the first reason for female and male alopecia. This pathology affects more than half of women over 50 and nearly 70% of men. The role of androgens has long been recognized. The gene that has an androgen receptor is located on the X chromosome and it is also one of the genes potentially announcing alopecia. The genes that can be found on chromosome 20 and specifically at 20p 11 are also indicative of a certain prognosis. In men, the increase in the production of 5-alpha-reductase causes a localized increase in the level of di-hydro-testosterone, which contributes in particular to the weakening of the hair. In women, the process remains relatively unproven, however, we often find the loss of the anti-androgenic action usually performed by estrogens following the menopause.

* Environmental Factors:

Beyond these hormonal and genetic causes, the hair is subject to a vast number ofenvironmental elements which increases their aging. These include, in particular, the sun, cosmetics, tobacco, manipulation of the scalp or even emotional and oxidative stress, among others... The aging of our hair is revealed in particular by a reduction in the growth phase, a reduction in the circumference of the hair shaft, bleaching and a drastic drop in elasticity. * Oxidative stress - mainly genetic cause: Oxidative stress increases this aging by reducing the anagen stage and by prematurely provoking the so-called 'catagen' phase which is illustrated by a fall in the peribulbar vascularization. Also, aging results in drop in glutathione concentration, the cell's main defense mechanism against stress in the hair follicle.

Alopecia and Scalp Aging: How to act?

Must therefore act on the extrinsic parameters (non-genetic) alopecia. Indeed, as with the skin of our face, the scalp is affected by aging. Also, it therefore seems normal to treat it and correct it (as far as possible) as we do for the skin: by meso-needling and/or by mesotherapy. This process aspires to deal with cellular aging at the level of the hair follicles by developing an effective action on the so-called 'environmental' factors of alopecia, particularly oxidative stress which is the main responsible for the known phenomena of alopecia.apoptosis (programmed cell death) and alteration of regular cellular processes leading to poor vascularization of the scalp. Meso-needling is applicable up to stage V in men with the appearance of a noticeable thinning of the vertex and the temporal gulfs. In effect, it is necessary that the existence of hair bulbs remains in order to carry out this treatment.

Alopecia and Scalp Aging: The hair cycle

The hair cycle is divided into three phases: Anagen – Catagen – Telogen La phase Anagen, this is the growth stage, it applies to 85% of the hair over an average period of 3 years. Period during which the hair grows 0.5 - 2 cm each month. The so-called phase of Catagen, which concerns 1% of the hair and lasts 3 weeks. The so-called phase of Telogen which represents a period of rest followed by a fall. It represents 14% of the hair over a period of 3 months. So the goal is to prevent the Catagen phase and prolong the Anagen phase.

Alopecia and Scalp Aging: Poly-revitalizing Solutions

Very often, conventional products do not bear fruit. Then comes the idea of adding a compound of micronutrients and antioxidants which, combined, helps prevent the disuse of the hair follicles and contributes to improving the quality and regrowth of hair: Vitamins E and C for their antioxidant actions. Glutathione to fight oxidative stress and maintain good microcirculation. The B vitamins required for the perpetuation of the hair follicle and to promote the synthesis of keratin. Vitamin B3 specifically for its properties allowing good vasodilation. Amino acids and minerals to compensate for deficiencies in the dermis and epidermis. Lately, hyaluronic acid, for its moisturizing effect and its definite contribution to cell proliferation and to the balance of the dermis.

So what is meso-needling..? Meso-needling consists of making absorb active ingredients through the skin using a roller. This reduces any hair loss and increases the vitality of the scalp.

Meso-Needling : Testimony of a Dermatologist

What is the interest of meso-needling? Meso-needling requires the use of a roller to increase the absorption of nutrients and antioxidants vital for hair regrowth. This technique induces 3 effects: 1) First of all, it increases the activity of the cells of the skin of the scalp following the penetration of the needles, it thus stimulates the fibroblasts which create all the more elastin and collagen . 2) Then, it allows the creation of micro-channels in order to improve the absorption of the active ingredients administered. 3) Finally, the meso-needling fluidifies the micro circulation of the treated area. Thus, meso-needling is also less painful, therefore less traumatic and less invasive than so-called 'classic' mesotherapy. Because, it is carried out by multiple injections either by gun or manually. Meso-needling is easier to perform. In what cases have you used it? I set it up on two distinct groups of subjects: The first made up of fairly young patients with limited damage to the temporal gulfs; the second with patients presenting an authentic androgenic alopecia either of grade III, IV, or even V according to the Hamilton scale. What is the protocol? A meso-needling session every 2 weeks for 3 months, then only one per month. A minimum of 10 sessions are required. After 9 months, an assessment is carried out to decide on the continuation of treatment.

From your own experience, what results can be expected?

In my case, the results were truly satisfactory in all patients. This was illustrated by a increase in hair density in the region of the temporal gulfs. Generally, subjects with localized and incipient alopecia have noticed an improvement in their hair. Subjects with alopecia at a more advanced stage were able to observe a noticeable hair growth. Meso-needling combined with a nutrient product rich in minerals, antioxidants and amino acids. Thanks to this, he brings results both on the plane preventive and therefore curative. This technique is a new advance in stopping hair loss and dealing with the aging of the scalp. It increases the quality of regrowth with enhanced capillary density. Is maintenance treatment necessary? For cases of androgenic alopecia, one session every two months gives lasting results. Thus, in the event of beginning thinning of the temporal gulfs, a single session every 3-4 months may be sufficient.

Alopecia and Scalp Aging: Our opinion

Paul LORHO (Manager of Centrale Fillers): Our selection fell on a well-known product in French pharmacies: Meso Needling from Filorga laboratories. Thus, Filorga, a pioneer in this field, offers a guarantee of quality because all its products are designed by world-renowned experts (doctors, pharmacists, biologists, cosmetologists) gathered within a scientific committee and are manufactured in France. Alopecia - The Filorga Pack Roller is the Perfect Tool Equipped with a head cylindrical shape with 600 ultra fine needles, mounted on a dozen independent records. There are two distinct widths of rollerblades marketed by Filorga laboratories. For large balding areas, the larger size should be used to improve treatment efficiency. As for the parts strewn with hair, the narrowest roller will allow a precise action, line by line. In practice, the skin must be carefully disinfected using chlorhexidine. Only then, the treatment solution will be deposited directly on the surface of the scalp. Only then should the roller be applied with a slight pressure according to so-called ‘multidirectional’ movements. Thus, it is recommended to carry out up to 6 passes for each area to be treated.

Source : C. Le Bihan – Androgenic Alopecia New meso-needling treatment strategies. Information communicated by the Filorga Laboratories.

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